Thesis on Oxidative Stress and "arteriosclerosis"
- Development Story
- About Oxidative stress
- About alcohol metabolism
- Basics of Antioxidant Research
- The relationship between reactive oxygen species (ROS) and disease
- Thesis on relevance between oxidative stress and disease
- Paper title
- [Can arteriosclerosis be prevented by antioxidants?].
- Abstract summary
- Antioxidants are clinically interesting antioxidants.
- B. Møgelvang
- Nordisk medicin
- Semantic Scholar URL
The very extensive research into atherogenesis carried out in recent years has yielded new knowledge of the importance of oxidation by free radicals of low-density lipoproteins and lipids, for instance in endothelial cell membrane. This has provided greater insight into the potential benefit of preventive measures using anti-oxidants to inhibit atherogenesis, and the results of clinical trials carried out so far would seem to confirm this. Prospective, controlled epidemiological trials are still lacking, but this will probably be remedied within the next 2-3 decades. The most clinically interesting antioxidants are vitamins C and E, beta-carotene, the ubiquinones, and the trace element selenium, substances that are naturally integrated components of the complex biochemistry of the human organism. The review is intended to clarify the scientific rationale for an increased intake of such anti-oxidants with a view to reducing the incidence of ischaemic vascular disorders.