What is the relationship between fatigue and oxidative stress? Fatigue and Oxidative Stress

March 24, 2021

What is the relationship between fatigue and oxidative stress? Fatigue and Oxidative Stress

In today’s society, many people are exposed to fatigue, such as fatigue from work, studying, housework, and nursing care.

 


“I want to be free from fatigue!” Fatigue is a sign of the body’s limitations and a signal to rest.

Fatigue and Lactic Acid

When some people hear the word “fatigue”, “lactic acid” may come to mind. There are people who say, “I have muscle pain due to lactic acid buildup”, especially after using muscles in exercise. The reason why lactic acid is said to be the cause of fatigue is based on the results of experiments conducted about 100 years ago.

However, recent research has shown that lactic acid is not the cause of fatigue, but a substance that helps to recover from fatigue.

Lactic acid is a substance that is released from muscle cells during exercise, but we know that it is changed in the body and converted into energy by mitochondria.

So what is the cause of fatigue? Fatigue is actually related to oxidative stress.


Fatigue and Oxidative Stress

The relationship between fatigue and oxidative stress can be thought of as a parallel relationship between the chicken and the egg.

When you think of “fatigue”, you often think of muscle fatigue after physical exertion, “I’m so tired!” But the truth is that at the same time as muscle fatigue, fatigue substances also accumulate in the brain.

Therefore, by suppressing oxidative stress, fatigue will be lowered. And naturally, as fatigue decreases, oxidative stress also decreases.

In the parallel relationship of “chicken first, egg second”, if one side goes down, the other side goes down, so lowering oxidative stress leads to lower fatigue, and lowering fatigue leads to lower oxidative stress.

In addition to physical fatigue, oxidative stress substances are also known to be involved in the cause of stiff shoulders.

We are currently collecting data related to oxidative stress when acupressure is used to relieve stiff shoulders, and we will report the results of our research when we have more detailed information on the mechanism.

Finally.

This article has explained that fatigue and oxidative stress are very much related.

Muscle pain is often caused by tearing of muscle fibers due to overuse, so resting the body without overexerting yourself will help you recover from fatigue. The best thing to do is to rest when you are in pain, because forcing yourself to move the part of your body that is in pain can prevent the muscle from repairing itself and can put stress on the surrounding joints.


When you feel tired both mentally and physically due to great stress, oxidative stress substances accumulate in your brain. In such cases, reducing oxidative stress can help reduce fatigue.

If you are suffering from chronic fatigue, which is a condition in which you cannot get rid of fatigue even if you sleep enough, or if you have not been able to get rid of fatigue for more than six months, the oxidative stress in your body will increase and you will be exposed to oxidative stress, which may lead to aging and illness.